25 percent don't complete recommended breast cancer treatment

Public release date: 9-Apr-2013
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Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Side effects cited as patients' most common reason for skipping hormone-blocking therapy or stopping early

April 9, 2013

ANN ARBOR, Mich. One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan Comprehensive Cancer Center researchers.

Five years of daily tamoxifen or aromatase inhibitors -- two types of endocrine therapy that are taken as a pill -- is recommended for many women whose breast cancer expresses the hormones estrogen or progesterone. The drugs have been shown to reduce cancer recurrence and increase survival. And recent studies suggest there may be even more benefit for some women to continue this therapy for 10 years.

Despite this, the study of 743 women eligible for endocrine therapy found that about 11 percent never initiated the treatments and 15 percent stopped taking it early. Results appear online in Breast Cancer Research and Treatment.

"We're doing well with women taking endocrine therapy, but there's work to do," says lead study author Christopher Friese, Ph.D., R.N., assistant professor at the University of Michigan School of Nursing. "If guidelines begin to shift so that some women at high risk of breast cancer recurring need 10 years of endocrine therapy, then the number of women who persist with treatment will likely worsen. We need to develop better ways of supporting women through this therapy."

The most common reason patients said they either discontinued or never started endocrine therapy was side effects. Many women experience menopause-like symptoms such as hot flashes or vaginal dryness, and both types of drugs, more commonly the aromatase inhibitors, can cause joint pains.

The study surveyed women in the Detroit and Los Angeles areas who were diagnosed with breast cancer and reported to Surveillance, Epidemiology and End Results, or SEER, tumor registries. Women were surveyed at about nine months after their diagnosis and again about four years later with questions about their use of tamoxifen or any type of aromatase inhibitor.

Women who expressed more worry about their cancer recurring were more likely to complete endocrine therapy, as were women who already took medication regularly.

Women who reported receiving less information about endocrine therapy were less likely to begin taking it, suggesting that doctors need to address patient education before treatment starts. Women who saw a breast surgeon as their primary follow-up, rather than a medical oncologist, were also less likely to begin endocrine therapy.

"It was particularly interesting that greater fear of recurrence was associated in our patient sample with greater adherence to endocrine therapy," says senior study author Jennifer J. Griggs, M.D., M.P.H., professor of internal medicine at the U-M Medical School and a medical oncologist who sees patients with breast cancer at the U-M Comprehensive Cancer Center.

"We don't want our patients living under a cloud of fear, so we need to develop creative ways to both reassure and motivate them. This means providing better education about the importance of staying on these medications and partnering with primary care and cancer doctors to help patients manage symptoms," Griggs adds.

###

Breast cancer statistics: 234,580 Americans will be diagnosed with breast cancer this year and 40,030 will die from the disease, according to the American Cancer Society

Additional authors: Yun Li, Ph.D.; Paul H. Abrahamse; Reshma Jagsi, M.D., D.Phil.; Nancy K. Janz, Ph.D.; Sarah T. Hawley, Ph.D.; Steven J. Katz, M.D., M.P.H., all from University of Michigan; T. May Pini, from M.D. Anderson Cancer Center; John J. Graff, Ph.D., from Cancer Institute of New Jersey; Ann S. Hamilton, Ph.D., from University of Southern California

Funding: National Cancer Institute grants R01 CA109696, R01 CA088370, K05 CA111340; National Institute for Nursing Research grant R00 NR01570; American Cancer Society

Disclosure: None

Reference: Breast Cancer Research and Treatment, DOI 10.1007/s10549-013-2499-9

For more information, contact: Nicole Fawcett

Resources:

U-M Cancer AnswerLine, 800-865-1125
U-M Comprehensive Cancer Center, http://www.mcancer.org
Clinical trials at U-M, http://www.UMClinicalStudies.org/cancer

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 9-Apr-2013
[ | E-mail | Share ]

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System

Side effects cited as patients' most common reason for skipping hormone-blocking therapy or stopping early

April 9, 2013

ANN ARBOR, Mich. One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan Comprehensive Cancer Center researchers.

Five years of daily tamoxifen or aromatase inhibitors -- two types of endocrine therapy that are taken as a pill -- is recommended for many women whose breast cancer expresses the hormones estrogen or progesterone. The drugs have been shown to reduce cancer recurrence and increase survival. And recent studies suggest there may be even more benefit for some women to continue this therapy for 10 years.

Despite this, the study of 743 women eligible for endocrine therapy found that about 11 percent never initiated the treatments and 15 percent stopped taking it early. Results appear online in Breast Cancer Research and Treatment.

"We're doing well with women taking endocrine therapy, but there's work to do," says lead study author Christopher Friese, Ph.D., R.N., assistant professor at the University of Michigan School of Nursing. "If guidelines begin to shift so that some women at high risk of breast cancer recurring need 10 years of endocrine therapy, then the number of women who persist with treatment will likely worsen. We need to develop better ways of supporting women through this therapy."

The most common reason patients said they either discontinued or never started endocrine therapy was side effects. Many women experience menopause-like symptoms such as hot flashes or vaginal dryness, and both types of drugs, more commonly the aromatase inhibitors, can cause joint pains.

The study surveyed women in the Detroit and Los Angeles areas who were diagnosed with breast cancer and reported to Surveillance, Epidemiology and End Results, or SEER, tumor registries. Women were surveyed at about nine months after their diagnosis and again about four years later with questions about their use of tamoxifen or any type of aromatase inhibitor.

Women who expressed more worry about their cancer recurring were more likely to complete endocrine therapy, as were women who already took medication regularly.

Women who reported receiving less information about endocrine therapy were less likely to begin taking it, suggesting that doctors need to address patient education before treatment starts. Women who saw a breast surgeon as their primary follow-up, rather than a medical oncologist, were also less likely to begin endocrine therapy.

"It was particularly interesting that greater fear of recurrence was associated in our patient sample with greater adherence to endocrine therapy," says senior study author Jennifer J. Griggs, M.D., M.P.H., professor of internal medicine at the U-M Medical School and a medical oncologist who sees patients with breast cancer at the U-M Comprehensive Cancer Center.

"We don't want our patients living under a cloud of fear, so we need to develop creative ways to both reassure and motivate them. This means providing better education about the importance of staying on these medications and partnering with primary care and cancer doctors to help patients manage symptoms," Griggs adds.

###

Breast cancer statistics: 234,580 Americans will be diagnosed with breast cancer this year and 40,030 will die from the disease, according to the American Cancer Society

Additional authors: Yun Li, Ph.D.; Paul H. Abrahamse; Reshma Jagsi, M.D., D.Phil.; Nancy K. Janz, Ph.D.; Sarah T. Hawley, Ph.D.; Steven J. Katz, M.D., M.P.H., all from University of Michigan; T. May Pini, from M.D. Anderson Cancer Center; John J. Graff, Ph.D., from Cancer Institute of New Jersey; Ann S. Hamilton, Ph.D., from University of Southern California

Funding: National Cancer Institute grants R01 CA109696, R01 CA088370, K05 CA111340; National Institute for Nursing Research grant R00 NR01570; American Cancer Society

Disclosure: None

Reference: Breast Cancer Research and Treatment, DOI 10.1007/s10549-013-2499-9

For more information, contact: Nicole Fawcett

Resources:

U-M Cancer AnswerLine, 800-865-1125
U-M Comprehensive Cancer Center, http://www.mcancer.org
Clinical trials at U-M, http://www.UMClinicalStudies.org/cancer

---

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?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-04/uomh-2dc040913.php

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Broadcasters worry about 'Zero TV' homes

This undated image provided by James Weitze shows a truck driver taking a self portrait on the road. Weitze satisfies his video fix with an iPhone. He sleeps most of the time in his truck, and has no apartment. To be sure, he's an extreme case and probably wouldn't fit into Nielsen's definition of a household in the first place. But he's watching Netflix enough to keep up on shows like ?Weeds,? ?30 Rock,? ?Arrested Development,? ?Breaking Bad,? ?It's Always Sunny in Philadelphia? and ?Sons of Anarchy.? (AP Photo/James Weitze)

This undated image provided by James Weitze shows a truck driver taking a self portrait on the road. Weitze satisfies his video fix with an iPhone. He sleeps most of the time in his truck, and has no apartment. To be sure, he's an extreme case and probably wouldn't fit into Nielsen's definition of a household in the first place. But he's watching Netflix enough to keep up on shows like ?Weeds,? ?30 Rock,? ?Arrested Development,? ?Breaking Bad,? ?It's Always Sunny in Philadelphia? and ?Sons of Anarchy.? (AP Photo/James Weitze)

LOS ANGELES (AP) ? Some people have had it with TV. They've had enough of the 100-plus channel universe. They don't like timing their lives around network show schedules. They're tired of $100-plus monthly bills.

A growing number of them have stopped paying for cable and satellite TV service, and don't even use an antenna to get free signals over the air. These people are watching shows and movies on the Internet, sometimes via cellphone connections. Last month, the Nielsen Co. started labeling people in this group "Zero TV" households, because they fall outside the traditional definition of a TV home. There are 5 million of these residences in the U.S., up from 2 million in 2007.

Winning back the Zero TV crowd will be one of the many issues broadcasters discuss at their national meeting, called the NAB Show, taking place this week in Las Vegas.

While show creators and networks make money from this group's viewing habits through deals with online video providers and from advertising on their own websites and apps, broadcasters only get paid when they relay such programming in traditional ways. Unless broadcasters can adapt to modern platforms, their revenue from Zero TV viewers will be zero.

"Getting broadcast programing on all the gizmos and gadgets ? like tablets, the backseats of cars, and laptops ? is hugely important," says Dennis Wharton, a spokesman for the National Association of Broadcasters.

Although Wharton says more than 130 TV stations in the U.S. are broadcasting live TV signals to mobile devices, few people have the tools to receive them. Most cellphones require an add-on device known as a dongle, but these gadgets are just starting to be sold.

Among this elusive group of consumers is Jeremy Carsen Young, a graphic designer, who is done with traditional TV. Young has a working antenna sitting unplugged on his back porch in Roanoke, Va., and he refuses to put it on the roof.

"I don't think we'd use it enough to justify having a big eyesore on the house," the 30-year-old says.

Online video subscriptions from Netflix Inc. and Amazon.com Inc. ? which cost less than $15 a month combined ? have given him and his partner plenty to watch. They take in back episodes of AMC's "The Walking Dead" and The CW's "Supernatural," and they don't need more, he says.

He doesn't mind waiting as long as a year for the current season's episodes to appear on streaming services, even if his friends accidently blurt out spoilers in the meantime. With regular television, he might have missed the latest developments, anyway.

"By the time it gets to me to watch, I've kind of forgotten about that," he says.

For the first time, TV ratings giant Nielsen took a close look at this category of viewer in its quarterly video report released in March. It plans to measure their viewing of new TV shows starting this fall, with an eye toward incorporating the results in the formula used to calculate ad rates.

"Our commitment is to being able to measure the content wherever it is," says Dounia Turrill, Nielsen's senior vice president of insights.

The Zero TV segment is increasingly important, because the number of people signing up for traditional TV service has slowed to a standstill in the U.S.

Last year, the cable, satellite and telecoms providers added just 46,000 video customers collectively, according to research firm SNL Kagan. That is tiny when compared to the 974,000 new households created last year. While it's still 100.4 million homes, or 84.7 percent of all households, it's down from the peak of 87.3 percent in early 2010.

Nielsen's study suggests that this new group may have left traditional TV for good. While three-quarters actually have a physical TV set, only 18 percent are interested in hooking it up through a traditional pay TV subscription.

Zero TVers tend to be younger, single and without children. Nielsen's senior vice president of insights, Dounia Turrill, says part of the new monitoring regime is meant to help determine whether they'll change their behavior over time. "As these homes change life stage, what will happen to them?"

Cynthia Phelps, a 43-year-old maker of mental health apps in San Antonio, Texas, says there's nothing that will bring her back to traditional TV. She's watched TV in the past, of course, but for most of the last 10 years she's done without it.

She finds a lot of programs online to watch on her laptop for free ? like the TED talks educational series ? and every few months she gets together with friends to watch older TV shows on DVD, usually "something totally geeky," like NBC's "Chuck."

The 24-hour news channels make her anxious or depressed, and buzz about the latest hot TV shows like "Mad Men" doesn't make her feel like she's missing out. She didn't know who the Kardashian family was until she looked them up a few years ago.

"I feel absolutely no social pressure to keep up with the Joneses in that respect," she says.

For Phelps, it's less about saving money than choice. She says she'd rather spend her time productively and not get "sucked into" shows she'll regret later.

"I don't want someone else dictating the media I get every day," she says. "I want to be in charge of it. When I have a TV, I'm less in control of that."

The TV industry has a host of buzz words to describe these non-traditionalist viewers. There are "cord-cutters," who stop paying for TV completely, and make do with online video and sometimes an antenna. There are "cord-shavers," who reduce the number of channels they subscribe to, or the number of rooms pay TV is in, to save money.

Then there are the "cord-nevers," young people who move out on their own and never set up a landline phone connection or a TV subscription. They usually make do with a broadband Internet connection, a computer, a cellphone and possibly a TV set that is not hooked up the traditional way.

That's the label given to the group by Richard Schneider, the president and founder of the online retailer Antennas Direct. The site is doing great business selling antennas capable of accepting free digital signals since the nation's transition to digital over-the-air broadcasts in 2009, and is on pace to sell nearly 600,000 units this year, up from a few dozen when it started in 2003.

While the "cord-nevers" are a target market for him, the category is also troubling. More people are raised with the power of the Internet in their pocket, and don't know or care that you can pull TV signals from the air for free.

"They're more aware of Netflix than they're aware over-the-air is even available," Schneider says.

That brings us to truck driver James Weitze. The 31-year-old satisfies his video fix with an iPhone. He often sleeps in his truck, and has no apartment. To be sure, he's an extreme case who doesn't fit into Nielsen's definition of a household in the first place. But he's watching Netflix enough to keep up with shows like "Weeds," ''30 Rock," ''Arrested Development," ''Breaking Bad," ''It's Always Sunny in Philadelphia" and "Sons of Anarchy."

He's not opposed to TV per se, and misses some ESPN sports programs like the "X Games."

But he's so divorced from the traditional TV ecosystem it could be hard to go back. It's become easier for him to navigate his smartphone than to figure out how to use a TV set-top box and the button-laden remote control.

"I'm pretty tech savvy, but the TV industry with the cable and the television and the boxes, you don't know how to use their equipment," he says. "I try to go over to my grandma's place and teach her how to do it. I can't even figure it out myself."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-04-07-Zero%20TV/id-da2c6d0410824dd78c34cd0b43d32716

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Louisville beats Michigan 82-76 to win NCAA title

ATLANTA (AP) ? Luke Hancock made all five of his 3-pointers and led Louisville to its first NCAA men's basketball championship since 1986 with an 82-76 victory over Michigan on Monday night.

Coach Rick Pitino added this title to the one he won at Kentucky in 1996 and is the first coach to win a championship at two schools. Earlier in the day, Pitino was elected to the Naismith Memorial Hall of Fame.

Hancock scored 22 points and Peyton Siva had 18 for the Cardinals (35-5), who trailed by 12 late in the first half before rallying for the school's third national title.

Trey Burke had 24 points for Michigan (31-8), which was in the final for the first time since the Fab Five led the Wolverines there in 1993. Little-used freshman Spike Albrecht added 17 points.

But the celebration belonged to the Cardinals, who added this to a Sugar Bowl victory this year and also have their women's team in Tuesday's national final against Connecticut.

Chane Behanan scored nine quick points early in the second half to help Louisville take the lead after trailing by double digits.

Behanan finished with 15 points and 13 rebounds, including eight on the offensive glass.

Albrecht came in for Burke and made his first four 3-point attempts, scoring all his points in the opening half. Albrecht finally missed with a little more than 11 minutes left; he was still 9 for 10 from long range for the tournament.

Hancock made all four of his 3-pointers to start a 14-1 run for Louisville that briefly gave the Cardinals a one-point lead late in the first half after they trailed by 12. Michigan's Glenn Robinson III made two free throws with 2 seconds left to give the Wolverines the lead at the half but Louisville led by as many as five early in the second.

The Cardinals came in having won six games this season after trailing by 10 or more, including Saturday night's semifinals, when they beat Wichita State 72-68 after also falling behind by 12.

It was a scintillating final act of a season that has been more of a grind, with scoring at its lowest (67.49 points per team) since 1951-52 and shooting at its worst (43.3 percent) since 1964-65.

The 131.2-points-per-game average during March Madness is the lowest since the 3-point line was brought to the game in 1987, though the teams had surpassed that with 5:30 left.

Sitting on the bench with the Cardinals was sophomore guard Kevin Ware, the team's inspiration since snapping his tibia in the regional final last weekend.

Needing a pickup without Ware, Hancock led the scoring against Wichita State. And rarely used walk-on Tim Henderson made two key 3-pointers during the comeback.

Pitino, meanwhile, was working the sideline hours after being chosen for the Naismith Memorial Hall of Fame.

Russ Smith, the Louisville team leader who Pitino has nicknamed "Russdiculous" for some of his wild ? and wildly effective ? antics on the court, finished with nine points on 3-of-16 shooting.

Michigan topped Syracuse 61-56 on Saturday despite an off night from Burke, who finished with only seven points on 1-for-8 shooting.

Burke, a sophomore, seriously considered leaving for the NBA after last season but decided he had unfinished business left in Ann Arbor. He picked up the AP Player of the Year award, among others, and is now one victory away from the ultimate prize in college hoops.

Source: http://news.yahoo.com/louisville-beats-michigan-82-76-win-ncaa-title-034922701--spt.html

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HBO Go version 2.1 for iOS adds AirPlay multitasking

Now that you can finally watch HBO Go on your Apple TV via AirPlay, the premium cable network has decided to sweeten its iOS app with AirPlay multitasking in a 2.1 update. The new version of the app also offers enhancements to Game of Throne's interactive features and general performance improvements as well. We'd obviously prefer that the app offers a standalone option instead, but being able to catch up on episodes of GoT on the HDTV while looking up how to say "winter is coming" in Dothraki is good too. (It's "Aheshke jada.")

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Source: HBO Go (iTunes)

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Pork found in Ikea's moose lasagna

STOCKHOLM (AP) ? Ikea says it has withdrawn 17,000 portions of moose lasagna from its home furnishings stores in Europe after traces of pork were found in a batch tested in Belgium.

Ikea spokeswoman Tina Kardum said the product had only been on sale for a month when it was pulled off the shelves on March 22.

The company didn't announce the withdrawal publicly until Swedish newspaper Svenska Dagbladet wrote about it Saturday.

Kardum said the company found out Friday that a follow-up test in Belgium confirmed the lasagna contained 1.6 percent pork.

"We have more information now. That's why we choose to inform now," Kardum said.

Moose meat is common in Sweden though it's not typically used in lasagna.

Ikea has previously recalled meatballs and other meat products sold in its cafeterias and frozen foods sections after tests showed they contained traces of horsemeat.

The Swedish furniture giant is one of many European companies caught up in a scandal over mislabeled meat in frozen food products.

Ikea's withdrawn products came from a Swedish frozen foods maker, which in turn blamed the mislabeling on its meat suppliers.

Source: http://news.yahoo.com/pork-found-ikeas-moose-lasagna-102028200--finance.html

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Fashion designer Lilly Pulitzer dies at 81

FILE - In this March 16, 1965 file photo, Palm Beach the fashion designer Lilly Pulitzer, wears her own design and creation of the Lilly shift, in Palm Beach, Fla. Pulitzer, known for her tropical print dresses, dies in Florida at 81. (AP Photo/Robert H. Houston, File)

FILE - In this March 16, 1965 file photo, Palm Beach the fashion designer Lilly Pulitzer, wears her own design and creation of the Lilly shift, in Palm Beach, Fla. Pulitzer, known for her tropical print dresses, dies in Florida at 81. (AP Photo/Robert H. Houston, File)

FILE - In this March 16, 1965 file photo, Palm Beach the fashion designer Lilly Pulitzer, wears her own design and creation of the Lilly shift, in Palm Beach, Fla. Pulitzer, known for her tropical print dresses, dies in Florida at 81. (AP Photo/Robert H. Houston, File)

MIAMI (AP) ? Lilly Pulitzer hosted parties in her bare feet and wasn't afraid to get a little messy ? just as long as she looked good and had fun, too.

In the late 1950s, the Palm Beach socialite had time to spare and a wealthy husband who owned citrus groves, so she opened an orange juice stand just off the island's main shopping street. Pulitzer needed to hide all the juice stains on her clothes, though. Instead of just putting on an apron, she asked her seamstress to make some sleeveless dresses in colorful fruit prints, and a fashion staple was born.

Pulitzer died at her home Sunday, according to Quattlebaum Funeral and Cremation Services. She was 81.

Pulitzer's tropical print dresses became a sensation in the 1960s when then-first lady Jacqueline Kennedy, who attended boarding school with Pulitzer, wore one of the sleeveless shifts in a Life magazine photo spread.

The colorful revolution came as fashion shed its reliance on neutrals, and Pulitzer's stuff was almost the housewife version of the more youthful mod look that was migrating from London.

To this day, the Lilly Pulitzer dress remains a popular, if not a necessary, addition to any woman's closet.

"I designed collections around whatever struck my fancy ... fruits, vegetables, politics, or peacocks! I entered in with no business sense. It was a total change of life for me, but it made people happy," Pulitzer, who married into the famous newspaper family, told The Associated Press in March 2009.

Pulitzer's dresses hung behind her juice stand and soon outsold her drinks. A boutique featuring the company's dresses ? developed with the help of partner Laura Robbins, a former fashion editor ? soon replaced the juice stand.

"Today we celebrate all that Lilly meant to us and come together as Lilly lovers to honor a true original who has brought together generations through her bright and happy mark on the world," James B. Bradbeer Jr. and Scott A. Beaumont, who bought the Lilly Pulitzer brand in 1992, said in a statement.

The signature Lilly palette features tongue-in-cheek jungle and floral prints in blues, pinks, light greens, yellow and orange ? the colors of a Florida vacation.

The line of dresses that bore her name was later expanded to swimsuits, country club attire, children's clothing, a home collection and a limited selection of menswear.

"Style isn't just about what you wear, it's about how you live," Pulitzer said in 2004.

"We focus on the best, fun and happy things, and people want that. Being happy never goes out of style," she said.

In 1966, The Washington Post reported that the dresses were "so popular that at the Southampton Lilly shop on Job's Lane they are proudly put in clear plastic bags tied gaily with ribbons so that all the world may see the Lilly of your choice. It's like carrying your own racing colors or flying a yacht flag for identification."

But changing taste brought trouble. Pulitzer closed her original company in the mid-1980s after filing for Chapter 11 bankruptcy. The label was revived about a decade later after being acquired by Pennsylvania-based Sugartown Worldwide Inc.; Pulitzer was only marginally involved in the new business but continued reviewing new prints from Florida.

"When Lilly started the business back in the '60s, she targeted a young customer because she was young," Bradbeer told the AP in 2003. "What we have done is target the daughter and granddaughter of that original customer."

Pulitzer herself retired from day-to-day operations in 1993, although she remained a consultant and a muse for the brand.

Sugartown Worldwide was bought by Atlanta-based Oxford Industries in 2010. Sales of the Lilly Pulitzer brand were strong in the earnings period that ended Feb. 2. The brand's revenue increased 26 percent to $29.1 million, according to Oxford Industries' earnings report. The company said last week it planned to add four to six new stores each year for its Lily Pulitzer brand.

Pulitzer was born Lilly McKim on Nov. 10, 1931, to a wealthy family in Roslyn, N.Y.

In 1952, she married Pete Pulitzer, the grandson of newspaper publisher Joseph Pulitzer, whose bequest to Columbia University established the Pulitzer Prize.

Pulitzer had three children in quick succession. After the third was born, she had a nervous breakdown and ended up in a mental hospital that catered to upscale clientele in New York. A doctor there told her that she needed to find a job.

"The doctor there said, 'You're not happy because you're not doing anything,' and I said, 'I don't know how to do anything.' I'd always had everything done for me, always had my nanny and my mummy making up my mind. The doctor said, 'You've got to go out and find something to do,'" Pulitzer told The New Yorker in 2000.

Pulitzer gave the same prescription to her friends. If one of them needed something to do, Pulitzer would open a store in her town.

The Pulitzers divorced in 1969. Pulitzer's second husband, Enrique Rousseau, died in 1993.

"I don't know how to explain what it was like to run my business, the joy of every day," she told Vanity Fair magazine in a story in 2003. "I got a kick every time I went into the shipping department. ... I loved seeing (the dresses) going out the door. I loved them selling in the shop. I liked them on the body. Everything. There's no explaining the fun I had."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-04-07-Lilly%20Pulitzer/id-d869a85b502642f8bed090099d0faae3

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Meow-Down For Jaime Pressly & Estella Warren!

Meow-Down For Jaime Pressly & Estella Warren!

Former “My Name is Earl” star Jaime Pressly and former model Estella Warren had their claws out on Friday night at Bootsy Bellows. The two stars got into a catfight over a stolen purse, ending up in the police being called as things became heated. Jaime Pressly and Estella Warren joined several other stars at ...

Meow-Down For Jaime Pressly & Estella Warren! Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/04/meow-down-for-jaime-pressly-estella-warren/

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